Alexander R. Keeble,
Nicholas T. Thomas,
Peyton J. Balawender,
Camille R. Brightwell,
Sara Gonzalez‐Velez,
Madeline G. O'Daniel,
Caitlin E. Conley,
Austin V. Stone,
Darren L. Johnson,
Brian Noehren,
Cale A. Jacobs,
Christopher S. Fry,
Allison M. Owen
Sergei Yanushkevich,
Aleksandra Zieminska,
Joshua Gonzalez,
Francisca Añazco,
Richard Song,
Alejandra Arias‐Cavieres,
Sara T. Granados,
Junyi Zou,
Yan Rao,
Axel R. Concepcion
Seyed Mohammadali Rahmati,
Alexander N. Klishko,
Ramaldo S. Martin,
Nate E. Bunderson,
Jeswin A. Meslie,
T. Richard Nichols,
Ilya A. Rybak,
Alain Frigon,
Thomas J. Burkholder,
Boris I. Prilutsky
Myocardial ischemia causes the production and release of metabolites such as bradykinin, which stimulates cardiac spinal sensory afferents, causing chest pain and an increase in sympathetic activity referred to as the cardiogenic sympathetic afferent reflex. While the brain stem nuclei, such as the nucleus tractus solitarius and rostral ventrolateral medulla, are essential in the cardiogenic […]
Prolonged sitting leads to a slumped posture, which indirectly influences spinal curvature and increases low back and hamstring stiffness. Active rather than passive recovery is an effective way to reduce the risks associated with such prolonged inactivity. However, it remains to be investigated which of the exercises frequently used for this purpose, the trunk stability […]
BackgroundRecurrent pregnancy loss (RPL) poses significant challenges in clinical management due to an unclear etiology in over half the cases. Traditional screening methods, including ultrasonographic evaluation of endometrial receptivity (ER), have been debated for their efficacy in identifying high-risk individuals. Despite the potential of artificial intelligence, notably deep learning (DL), to enhance medical imaging analysis, […]
IntroductionTemperature and oxygen are two factors that profoundly affect survival limits of animals; too much or too little of either is lethal. However, humans and other animals can exhibit exceptional survival when oxygen and temperature are simultaneously low. This research investigates the role of oxygen in the cold shock death of Caenorhabditis elegans.MethodsThe survival of […]
The assessment of vascular accessibility in patients undergoing hemodialysis is predominantly reliant on manual inspection, a method that is associated with several limitations. In this study, we propose an alternative approach by recording the acoustic signals produced by the arteriovenous fistula (AVF) and employing deep learning techniques to analyze these sounds as an objective complement […]
ObjectiveMeta-analysis was used to evaluate the effects of an exercise intervention on bone mineral content (BMC), bone mineral density (BMD), and bone metabolism in adolescents.MethodsA systematic search of PubMed, Embase, Cochrane Library, and Web of Science for RCTs on “exercise, adolescents, BMD, bone metabolism” up to 10 September 2024. Included RCTs focused on effects of […]
ObjectiveTo explore the feasibility of post-exercise heart rate recovery indicators for predicting maximum oxygen uptake (VO2max) in healthy adults aged 30–60 years.Methods260 healthy adults who did not perform regular exercise were randomly recruited and divided into a model group (n = 200) and a verification group (n = 60). Measure body fat percentage, weight, height and […]
IntroductionSkeletal muscle satellite cells (MuSCs or stem cells) play a crucial role in muscle development, maintenance, and regeneration, supporting both hypertrophy and regenerative myogenesis. Syndecans (SDCs) act as communication bridges within the muscle microenvironment, regulating interactions with extracellular matrix components and contributing significantly to tissue repair and inflammation. Specifically, syndecan-4 (SDC4) is involved in muscle […]
PurposeTo examine the effects of structured aerobic exercise on 24-hour mean blood glucose outcomes assessed by continuous glucose monitors in adults with type 2 diabetes.MethodsThe study established specific inclusion and exclusion criteria and conducted a comprehensive search across five databases, including PubMed, Web of Science, Embase, Cochrane Library, and EBSCOhost from the start year of […]
Excessive water consumption from liquid or reconstituted oral nutrition supplements may increase risk of fluid overload in renal patients. Nutri-jelly, a ready-to-eat texture-modified diet with 52.8% water, some protein, low potassium, phosphorus, and sodium, could be an alternative. However, its safety is unknown for adults undergoing hemodialysis (HD). This study investigated the short-term physiological safety […]
The essence of menopause is ovarian failure, decreased estrogen volatility, and deficiency leading to multiple related symptoms and an increased risk of metabolic disease in women, such as cardiovascular disease and osteoporosis. This study screened 773 eligible postmenopausal and perimenopausal women from an initial pool of 1187 participants, and various physiological and biochemical indices were […]
INTRODUCTION: The intricate habitats of aquatic organisms, coupled with the prevalence of pathogens, contribute to a high incidence of various diseases, particularly bacterial infections. Consequently, the formulation of sustainable and effective disease management strategies is crucial for the thriving aquaculture sector.
CONCLUSION: For Stand-Alone OLIF surgery, inserting the cage in the central anterior-posterior position of the intervertebral space and selecting a cage with a height not exceeding 12 mm can reduce the stress on the endplate after surgery, which is more conducive to the stability of the lumbar spine postoperatively and reduces the risk of postoperative […]
CONCLUSION: This study uncovered the dynamic changes in metabolism and immune responses of striped hamsters parasitized by Xenopsylla cheopis. Hosts adjust their physiological and immune states to optimize survival strategies during different ectoparasite stages, enhancing our understanding of host-ectoparasite interactions. This also paves the way for further research into how hosts regulate complex biological processes […]
CONCLUSION: Age, lower educational attainment, malnutrition, and depression are significant risk factors for CF. Moreover, mitochondrial dysfunction, characterized by decreased mtDNAcn, impaired respiratory function and increased ROS levels appears to be a critical phenotype of CF.
Chronic kidney disease (CKD) represents a significant global public health burden, affecting over 10% of the world's population. Its high morbidity, multifactorial complications, and substantial mortality impose significant burdens on healthcare systems and patients, necessitating considerable investment in healthcare resources. Renal fibrosis (RF) is a key pathological feature and driver of CKD progression. Extensive research […]
The field of competitive swimming lacks broadly applicable predictive models for talent identification across various age groups of adolescent swimmers. This study aimed to construct a predictive model for athletic talent using machine learning methods based on anthropometric and physiological data. Baseline data were collected from 5444 participants aged 10-18 in Shanghai, China, between 2015 […]
CONCLUSION: This study highlighted the efficacy of ailanthone against HCC and elucidated its underlying molecular mechanisms, suggesting the promising therapeutic potential of ailanthone for HCC.
The phenomenon of neural plasticity pertains to the intrinsic capacity of neurons to undergo structural and functional reconfiguration through learning and experiential interaction with the environment. These changes could manifest themselves not only as a consequence of various life experiences but also following therapeutic interventions, including the application of noninvasive brain stimulation (NIBS) and psychotherapy. […]